Felodipine, Thermo Scientific Chemicals

Description

A dihydropyridine calcium channel blocker

Felodipine is used as a dihydropyridine calcium channel blocker. It displays high vascular selectivity; lowers arterial blood pressure without altering cardiac contractility. Antihypertensive.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Felodipine is used as a dihydropyridine calcium channel blocker. It displays high vascular selectivity; lowers arterial blood pressure without altering cardiac contractility. Antihypertensive.

Solubility
Soluble in DMSO. Insoluble in water

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Keep away from strong oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 72509-76-3
• Molecular Formula: C18H19Cl2NO4
• Molecular Weight (g/mol): 384.253
• MDL Number: MFCD00868316
• InChI Key: RZTAMFZIAATZDJ-UHFFFAOYSA-N
• Synonym: felodipine, plendil, flodil, munobal, renedil, dl-felodipine, perfudal, splendil, feloday, prevex
• PubChem CID: 3333
• ChEBI: CHEBI:585948
• IUPAC Name: 5-O-ethyl 3-O-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
• SMILES: CCOC(=O)C1=C(NC(=C(C1C2=C(C(=CC=C2)Cl)Cl)C(=O)OC)C)C

• Color: Yellow
• Quantity: 50 mg
• Merck Index: 14,3953
• Solubility Information: Soluble in DMSO; Insoluble in water
• Formula Weight: 384.25
• Physical Form: Crystalline Powder
• Chemical Name or Material: Felodipine

Safety and Handling

Hazard Category	H302
Hazard Statement	GHS H Statement H302 Harmful if swallowed.
Precautionary Statement	P264b-P270-P301+P312-P330-P501c
RTECSNumber	US7968700
TSCA	No
Recommended Storage	Keep cold

SDS

RUO – Research Use Only